Here, We show that functionalization of the 4-arylidene position of the fluorescent curcumin scaffold with an aryl nitrogen mustard provides a stable Hck inhibitor (Kd = 50 ± 10 nM). The mustard curcumin derivative preferentially interacts with the inactive conformation of Hck, similar to type-II kinase inhibitors that are less https://bets10orjinalsitesi.isblog.net/5-вторых-трик-bäçlnk-päķtlêrí-50052139